Promoted Pescara will start the 2012/13 Serie A season with a two-point deduction for their involvement in alleged match-fixing.
Pescara's punishment is just one of the 72 rulings made on Monday by the Disciplinary Committee of the Italian Football Federation (FIGC) following an investigation called 'Last Bet'.
The inquiry has focused on 33 games over the past two seasons, the majority of which were in Serie B and the Coppa Italia but none in Serie A.
Atalanta, who finished 12th in Italy's top flight last season, have been docked two points and fined 25,000 euros.
Novara, who were relegated to the second tier last month, have been handed a four-point deduction for the start of their campaign and hit with a 35,000 euros fine.
Reggina will also start the Serie B season with a four-point deduction. Serie A side Siena and recently-promoted Sampdoria have both been fined 50,000 euros.
Former Inter Milan, Parma, Roma and Ternana defender Luigi Sartor was banned for five years, as were Nicola Santoni, Piacenza's Mario Cassano and Ravenna's Alessandro Zamperini.
Ex-AC Milan midfielder Tomas Locatelli has received a two-year ban along with former Atalanta captain Cristiano Doni.
Former Fiorentina midfielder Alberto Santana and ex-Inter Milan and Torino striker Nicola Ventola have been suspended for three years and six months, respectively.
The allegations for Atalanta, Novara and Siena stem from when they played in Serie B in past seasons.
The investigation is ongoing and more punishments are expected in the coming months.
The rulings have taken some of the attention away from Italy's national team, who are competing at the European Championship in Poland and Ukraine.
The Azzurri play against the Republic of Ireland tonight in a game they must win to have a chance to advance to the quarter-finals of the competition.