Lille boss Rudi Garcia wants his side to capitalise on the inaction of their rivals when they travel to Ligue 1's basement boys Sochaux on Wednesday.
Reigning champions Lille look rank outsiders to retain their title at the moment, with Paris St Germain and Montpellier nine and eight points ahead respectively.
They returned to winning ways at the weekend with a 1-0 win over Lorient, only their second victory from their last six league matches, and Garcia is looking for more of the same on Wednesday in a game rearranged from earlier this month.
He told a press conference: "We know that each point is hard to take, and this will be the same in Sochaux. Now we need to start a positive run.
"We are the only team at the head of the table to play and we will have an opportunity to get close to Montpellier and Paris."
Sochaux need points for a very different reason after they missed the chance to jump off the bottom of the table at the weekend when they could only draw with fellow strugglers Auxerre.
Striker Sloan Privat is confident things will turn around for Sochaux, although he admits they have a tough task on Wednesay.
"This is the champion team in France, a team that is always dangerous and difficult to play," he told www.fcsochaux.fr. "We will do everything to achieve something against them.
"We must make the most of the opportunities we have. If we continue to play the way we did on Saturday, it will eventually pay off."
Lille are likely to be without Florent Balmont after he picked up an injury at the weekend while Steven Mouyokolo, Yassin Mikari and Loic Pujol are all unavailable for Sochaux.
Teenager Yoann Collas will make his first appearance for the hosts in goal with Papa Demba Camara and Teddy Richert both out while Mali striker Modibo Maiga has returned to France after suffering a bout of malaria at the African Nations Cup and will be assessed by doctors.